Published January 1, 2016
| Version v1
Journal article
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Chemotherapeutic potentials of the stem bark of Balanite aegyptiaca (L.) Delile: an antiangiogenic, antitumor and antioxidant agent
Creators
- 1. Univ Sains Malaysia, Sch Pharmaceut Sci, EMAN Res & Testing Lab, Usm 11800, Penang, Malaysia
- 2. Alzaiem Alazhari Univ, Dept Chem, POB 1432, Khartoum 13311, Sudan
- 3. Univ Sains Malaysia, Dept Pharmaceut Chem, Sch Pharmaceut Sci, George Town 11800, Malaysia
- 4. Australian Natl Univ, ACRF Dept Canc Biol & Therapeut, John Curtin Sch Med Res, Canberra, Malaysia
- 5. Quest Int Univ, Dept Pharmacol, Perak, Malaysia
Description
Background: Balanite aegyptiaca (L.) Delile, is a plant with extensive medicinal properties. Its stem bark is traditionally known for its spasmolytic and antiepileptic properties and used to treat yellow fever, jaundice and syphilis. Angiogenesis (sprouting of new blood vessels) is crucial for tumor growth and metastasis. The goal of this study is investigate the antiangiogenic, cytotoxicity and antioxidant activity as well as antitumor in vivo properties of B. aegyptiaca stem bark extracts.
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