Yayınlanmış 1 Ocak 2016
| Sürüm v1
Dergi makalesi
Açık
Flufenamic acid prevents behavioral manifestations of salicylate-induced tinnitus in the rat
- 1. Gaziantep Univ, Dept Physiol, Fac Med, TR-27310 Gaziantep, Turkey
- 2. Firat Univ, Fac Vet, Dept Anat, TR-23169 Elazig, Turkey
- 3. Kirikkale Univ, Dept Med Biol, Fac Med, Kirikkale, Turkey
- 4. Firat Univ, Dept Neurol, Fac Med, Elazig, Turkey
- 5. Firat Univ, Dept Plast Reconstruct & Esthet Surg, Fac Med, Elazig, Turkey
Açıklama
Introduction: Tinnitus is defined as a phantom auditory sensation, the perception of sound in the absence of external acoustic stimulation. Given that flufenamic acid (FFA) blocks TRPM2 cation channels, resulting in reduced neuronal excitability, we aimed to investigate whether FFA suppresses the behavioral manifestation of sodium salicylate (SSA)-induced tinnitus in rats.
Dosyalar
bib-0531f0a8-8287-4382-9089-8619b239b0ef.txt
Dosyalar
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