Published January 1, 2016 | Version v1
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Synthesis of aminomethyl quinazoline based ruthenium (II) complex and its application in asymmetric transfer hydrogenation under mild conditions

  • 1. Kahramanmaras Sutcu Imam Univ, Dept Chem, Fac Sci & Letters, TR-46100 Kahramanmaras, Turkey
  • 2. Osmaniye Korkut Ata Univ, Fac Sci & Letters, Dept Chem, TR-80000 Osmaniye, Turkey

Description

The new chiral aminomethyl quinazoline (amq) type ligand derived from L-phenylalanine was synthesized and coordinated with [RuCl2(PPh3) dppb] to obtain ruthenium(II) complex. This catalyst displayed considerable reactivity (up to 97% ee and 99% conversion) in the asymmetric transfer hydrogenation of ketones using 2-propanol as a hydrogen source in the presence of NaOiPr. (C) 2016 Elsevier B.V. All rights reserved.

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