Yayınlanmış 1 Ocak 2016
| Sürüm v1
Dergi makalesi
Açık
Facile synthesis of the azocino[4,3-b]indole framework of strychnopivotine and other Strychnos alkaloids
Oluşturanlar
- 1. Namik Kemal Univ, Dept Chem, TR-59030 Tekirdag, Turkey
- 2. Namik Kemal Univ, Dept Chem Technol, TR-59700 Muratli Tekirdag, Turkey
- 3. Hitit Univ, Dept Chem, TR-19030 Corum, Turkey
Açıklama
A new synthetic route to the 1,5-methanoazocino[4,3-b]indole is described. The aim of the present study is to provide a tetracyclic skeleton for the synthesis of pentacyclic Strychnos alkaloids (tubifolidine and strychnopivotine). Starting from a carbazole derivative, the ring closure was achieved by an intramolecular aldol reaction. The final product was obtained in 45% in the overall yield over 7 steps.
Dosyalar
bib-cda41ac8-d93a-445b-b521-b15a9e3d3bb6.txt
Dosyalar
(213 Bytes)
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md5:53eb74f41f1d4cfcd980806b29030470
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