Published January 1, 2016
| Version v1
Journal article
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Deregulated Levels of the NF-kappa B1, NF-kappa B2, and Rel Genes in Ukrainian Patients with Leukemia and Lymphoma in the Post-Chernobyl Period
Creators
- 1. Kocaeli Univ, Dept Med Genet, Fac Med, Kocaeli, Turkey
- 2. Natl Acad Sci Ukraine, RE Kavetsky Inst Expt Pathol Oncol & Radiobiol, Kiev, Ukraine
Description
Objective: Nuclear factor kappa B (NF-kappa B) is an important transcription factor in cancer and NF-kappa B activation has been seen in angiogenesis, tumor progression, and metastasis. Relationships between specific NF-kappa B gene networks, leukemogenesis, and radiation exposure are still unknown. Our aim was to study the expression levels of the NF-kappa B1, NF-kappa B2, and Rel genes in hematological malignancies in the post-Chernobyl period.
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