Pharmacokinetic and pharmacodynamic evaluation of sublingual sufentanil in the treatment of post-operative pain

Introduction: Intravenous patient-controlled analgesia using opioids is frequently used to provide perioperative analgesia. However, there are a number of drawbacks for intravenous patient-controlled analgesia. The sufentanil sublingual tablet system is a major evolution in technology and drug development for postoperative pain management.