Yayınlanmış 1 Ocak 2016
| Sürüm v1
Dergi makalesi
Açık
A diagnostic tool for population models using non-compartmental analysis: The ncappc package for R
Oluşturanlar
- 1. Uppsala Univ, Dept Pharmaceut Biosci, POB 591, SE-75124 Uppsala, Sweden
Açıklama
Background and objective: Non-compartmental analysis (NCA) calculates pharmacokinetic (PK) metrics related to the systemic exposure to a drug following administration, e.g. area under the concentration time curve and peak concentration. We developed a new package in R, called ncappc, to perform (i) a NCA and (ii) simulation-based posterior predictive checks (ppc) for a population PK (PopPK) model using NCA metrics.
Dosyalar
bib-da7417a5-fb82-4454-9402-d7c1d2f11ebe.txt
Dosyalar
(240 Bytes)
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240 Bytes | Ön İzleme İndir |