Published January 1, 2016
| Version v1
Journal article
Open
A diagnostic tool for population models using non-compartmental analysis: The ncappc package for R
Creators
- 1. Uppsala Univ, Dept Pharmaceut Biosci, POB 591, SE-75124 Uppsala, Sweden
Description
Background and objective: Non-compartmental analysis (NCA) calculates pharmacokinetic (PK) metrics related to the systemic exposure to a drug following administration, e.g. area under the concentration time curve and peak concentration. We developed a new package in R, called ncappc, to perform (i) a NCA and (ii) simulation-based posterior predictive checks (ppc) for a population PK (PopPK) model using NCA metrics.
Files
bib-da7417a5-fb82-4454-9402-d7c1d2f11ebe.txt
Files
(240 Bytes)
| Name | Size | Download all |
|---|---|---|
|
md5:a3e86df7b97bdca7ae2172a867af3019
|
240 Bytes | Preview Download |