Yayınlanmış 1 Ocak 2016
| Sürüm v1
Dergi makalesi
Açık
Synthesis, antibacterial and antifungal evaluation of thio- or piperazinyl-substituted 1,4-naphthoquinone derivatives
Oluşturanlar
- 1. Istanbul Univ, Fac Engn, Dept Chem, Istanbul, Turkey
- 2. Istanbul Univ, Hasan Ali Yucel Educ Fac, Div Sci Educ, Dept Elementary Educ, Istanbul, Turkey
- 3. Istanbul Univ, Fac Engn, Dept Engn Sci, Istanbul, Turkey
- 4. Natl Univ Lviv Polytech, Dept Technol Biol Act Subst Pharm & Biotechnol, Lvov, Ukraine
Açıklama
A series of S-, S,S-, S,O-, N- and N,S-derivatives from 2,3-dichloro-1,4-naphthoquinone compound 1 were synthesized in different reaction media and evaluated for their antibacterial and antifungal activities. The structures of the novel products were characterized by spectroscopic methods, such as microanalysis, H-1 NMR, C-13 NMR and MS. Among the tested compounds 9, 12 and 18 are the most effective compounds against Candida tenuis as potent antifungal compounds. Compound 9 is also the most effective compound against Staphylococcus aureus as a potent antifungal compound.
Dosyalar
bib-165b9bdc-d8fb-4e92-a774-bca2f33e6765.txt
Dosyalar
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