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Published January 1, 2017 | Version v1
Journal article Open

Microarray Analysis of the Genes Associated With Osteitis in Chronic Rhinosinusitis

Creators

  • 1. Adnan Menderes Univ, Dept Otolaryngol Head & Neck Surg, Aydin, Turkey
  • 2. Harvard Med Sch, Massachusetts Eye & Ear Infirm, Dept Otolaryngol Head & Neck Surg, Boston, MA USA
  • 3. Adnan Menderes Univ, Dept Med Genet, Aydin, Turkey
  • 4. Adnan Menderes Univ, Dept Med Pathol, Aydin, Turkey

Description

Objectives/Hypothesis: Although numerous studies have examined epithelial remodeling in chronic rhinosinusitis (CRS), bone remodeling (osteitis) has only recently gained attention as a potential significant contributor to the pathophysiology of recalcitrant CRS. The purpose of this study was to compare gene expression profiles between osteitic bone and the adjacent diseased mucosa in patients with CRS to determine which genes affect mucosal and bony remodeling.

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