Yayınlanmış 1 Ocak 2017 | Sürüm v1
Dergi makalesi Açık

Structure-Based Hybridization, Conventional and Microwave Irradiated Synthesis, Biological Evaluation and Molecular Docking Studies of New Compounds Derived from Thiomorpholin

  • 1. Giresun Univ, Bulancak Kadir Karabas Sch Appl Sci, Dept Crop Prod & Technol, TR-28000 Giresun, Turkey
  • 2. Gebze Tech Univ, Fac Sci, Dept Chem, TR-41400 Kocaeli, Turkey
  • 3. Karadeniz Tech Univ, Dept Biol, TR-61080 Trabzon, Turkey
  • 4. Recep Tayyip Erdogan Univ, Dept Biol, TR-53100 Rize, Turkey
  • 5. Karadeniz Tech Univ, Dept Chem, TR-61080 Trabzon, Turkey

Açıklama

Background: The amine 2 obtained via two steps starting from thiomorpholine was converted into the corresponding 1,3-thiazole (4), arylmethileneamino (5a- d) and hydrazide (7) derivatives using conventional and also microwave techniques. The synthesis of 1,3,4-oxadiazole (8), arylidenenhydrazide (9a-c) and carbothioamides (10a,b) was performed with the treatment of 7 with CS2, suitable amines and suitable isothiocyanates, respectively.

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bib-332c7d28-e84d-446e-ae2b-5c74b7cee411.txt

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md5:8afa79e80781b94db185f92949f1bd09
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