ANALYSIS OF THE DIELECTROPHORETIC (DEP) SPECTRA OF BIOLOGICAL CELLS

This study presents an approach for analyzing the dielectrophoretic (DEP) spectra of biological cells without ascertaining their membrane and cytoplasmic properties. DEP spectrum device with reciprocal V-shaped planar-electrodes was utilized to obtain DEP spectra information of cells. Integrating electric field simulations based on a strong theory with the experimental data enables determination of the DEP spectrum at a range of frequencies, for the first in the literature. The proposed method is tested with MCF7 breast cancer cells and DEP spectra are obtained for 15 different frequencies in the range from 100 kHz to 50 MHz at 10 V-pp.