Published January 1, 2017 | Version v1
Journal article Open

Genotypes of hepatitis a virus in Turkey: first report and clinical profile of children infected with sub-genotypes IA and IIIA

  • 1. Istanbul Univ, Vet Fac, Dept Virol, Istanbul, Turkey
  • 2. Istanbul Univ, Cerrahpasa Fac Med, Dept Microbiol, Istanbul, Turkey
  • 3. Univ Izmir, Dept Child Hlth & Dis, Fac Med, Izmir, Turkey
  • 4. Sisli Hamidiye Etfal Training & Res Hosp, Div Infect Dis & Clin Microbiol, Istanbul, Turkey
  • 5. Dicle Univ, Dept Microbiol, Fac Med, Diyarbakir, Turkey
  • 6. Univ Harran, Dept Microbiol, Fac Med, Urfa, Turkey
  • 7. Kansas State Univ, Coll Vet Med, Dept Diagnost Med & Pathobiol, Manhattan, KS 66506 USA

Description

Background: Hepatitis A virus (HAV) is a food and water-borne virus causing clinical (mainly hepatitis) and subclinical disease in humans. It is important to characterize circulating strains of HAV in order to prevent HAV infections using efficacious vaccines. The aim of this study was the detection and characterization of the circulating strains of HAV in Turkey by performing serology, RT-PCR, sequencing and phylogenetic analysis.

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