Published January 1, 2017
| Version v1
Journal article
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THE STUDY OF SYNTETIC PEPTIDE LOADED PLGA NANOPARTICLES CYTOTOXICITY IN VITRO
Creators
- 1. Yildiz Tech Univ, Chem & Met Fac, Dept Bioengn, TR-34220 Istanbul, Turkey
- 2. Istanbul Yeni Yuzyil Univ, Fac Engn & Architecture, Dept Biomed Engn, TR-34010 Istanbul, Turkey
- 3. Yildiz Tech Univ, Art & Sci Fac, Mol Biol & Genet Dept, TR-34220 Istanbul, Turkey
Description
Canine parvovirus (CPV) is a viral disease which is seen widely worldwide and infects puppies. Current vaccines which developed against this infection have several disadvantages. The antigenic property of different peptide sequences on VP2 capsid protein which belongs to CPV has been shown in different studies. However, carriers or adjuvants are also required for peptide antigens which have small molecular size and weak immunogenicity.
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