Further Guaianolides from Chrysophthalmum montanum

Five new guaiane type sesquiterpene lactones; 6 beta-hydroxy-guai-9(10)-en-12,8 beta-olide-4 beta-O-beta-glucopyranoside (1), 6 beta-acetoxy-guai-9(10)-en-12,8 beta-olide-4 beta-O-beta-glucopyranoside (2), 5 alpha,10 beta-dihydroxy-guai-1(2)-en-12,8 beta-olide (3), 4 beta-hydroxy-guai-1(2)-en-12,8 beta-olide-10 beta-O-beta-glucopyranoside (4a), 1 alpha,4 alpha,10 beta-trihydroxy-guaian-12,8 beta-olide (5) were identified in the repeated examination of the aerial parts of the Chrysophthalmum montanum (DC) Boiss. The structures of the isolated compounds were elucidated by extensive 1D- and 2D-NMR spectroscopic analyses in combination with HRESIMS experiments.