Free Radical Scavenging Capacity and Antibacterial Activity of Wild Cirsium creticum from Turkey

Background: In recent years, there is increasing interest the using of herbal extracts derived from plants in medicine and as a dietary supplements. Objective: We aimed the determination of the antioxidant and antibacterial activity of Cirsium creticum (Lam) d'Urv. subsp. creticum included Asteraceae family which is wild plant species in Trakya region. Methods: Crude n-hexane, diethyl ether, ethylacetate and methanol extracts from whole plants was used the determination of antiradical and antibacterial activity in C. creticum and compared in terms of extracts efficiency. Results: EC50 values of DPPH activity in different solvents revealed significant differences similar to TPC content. The lowest inhibitory effect was found to be Gram negative for E. coli, despite the highest inhibitory effect against Gram positive S. aureus. Conclusion: Antiradical and antimicrobial activity results presented that C. creticum, could be evaluate in food supplements and pharmaceutical industry as natural compound, and future investigations will be aimed the isolations of biologically active compounds to define individual active components.