Synthesis of novel nitroso acetal derivatives via tandem 6 pi-electrocyclization/ [3+2]-cycloaddition of 1-nitro-2-methyl-1,3 butadiene

Novel nitroso acetal derivatives (4-methyl-2,3,3a,6-tetrahydroisoxazolo[2,3-b][1,2]oxazine) were synthesized through 6 pi-electrocyclization/[3+2]-cycloaddition reaction of several dionophiles with 1-nitro-2-methyl-1,3-butadiene. Structures of the synthesized compounds were determined by H-1-NMR, C-13-NMR, IR and GC-MS analyses.