Published January 1, 2017 | Version v1
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Strain-Specific Impact of Fusobacterium nucleatum on Neutrophil Function

  • 1. Forsyth Inst, Ctr Periodontol, Dept Appl Oral Sci, Cambridge, MA USA

Description

Background: Neutrophil function is critical for initiation and progression of infecto-inflammatory diseases. Key quorum-sensing plaque bacteria, such as Fusobacterium nucleatum, act as bridging species between early and late colonizer pathogens, such as Porphyromonas gingivalis, as the biofilm ages and periodontal inflammation increases. This study is designed to determine impact of different F. nucleatum strains on neutrophil function.

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