Published January 1, 2017 | Version v1
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The extracellular signal-regulated kinase 1/2 triggers angiogenesis in human ectopic endometrial implants by inducing angioblast differentiation and proliferation

  • 1. Univ S Florida, Dept Obstet & Gynecol, Morsani Coll Med, Tampa, FL 33620 USA
  • 2. Yale Univ, Sch Med, Dept Obstet Gynecol & Reprod Sci, New Haven, CT USA

Description

Problem: The role of extracellular signal-regulated kinase (ERK) 1/2-mediated angiogenesis during endometriotic nidation is unknown. We posit that ERK1/2-induced angioblast differentiation and proliferation promotes ectopic endometrial angiogenesis.

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