Published January 1, 2017 | Version v1
Journal article Open

Increased expression of YAP1 in prostate cancer correlates with extraprostatic extension

  • 1. Istanbul Medeniyet Univ, Fac Engn & Nat Sci, Mol Biol & Genet Dept, TR-34700 Istanbul, Turkey
  • 2. Istanbul Medeniyet Univ, Dept Pathol, Fac Med, TR-34700 Istanbul, Turkey
  • 3. Univ Calif Riverside, Dept Stat, Riverside, CA 92521 USA

Description

Objective: Yes associated protein 1 (YAP1) is a member of the Hippo pathway, acting as a transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p) YAP1 in prostate cancer (PCa) tumorigenesis, we investigated their expression in clinical samples of PCa and cell lines.

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