Published January 1, 2017 | Version v1
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Copper-catalyzed N-H/S-H functionalization: A strategy for the synthesis of benzothiadiazine derivatives

  • 1. Erciyes Univ, Dept Pharmaceut Basic Sci, Fac Pharm, TR-03839 Kayseri, Turkey

Description

A copper-mediated N-S bond-forming reaction via N-H/S-H activation is described. This reaction occurs under mild conditions with high efficiency, step economy, and tolerates a wide variety of functional groups, providing an efficient means of accessing biologically important 1,2,4-benzothiadiazin-3(4H)-ones. (C) 2017 Elsevier Ltd. All rights reserved.

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