Biochemical and Histopathological Effects of in Utero Di-N-Hexyl Phthalate and Di-Cyclohexyl Phthalate Exposure on the Thyroid Axes and T3, T4, TSH Hormone Levels of Male and Female Rats: at Adulthood

Objective: To investigate the effects of di-n-hexyl phthalate (DHP) and dicyclohexyl phthalate (DCHP) on hypophysis/ thyroid axis in utero, pregnant rats were exposed to DHP or DCHP at doses of 0, 20, 100, and 500 mg/kg bw/d, by gavage, on gestational days (GD) 6-19.