Published January 1, 2008
| Version v1
Journal article
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Carbamylated low-density lipoprotein induces proliferation and increases adhesion molecule expression of human coronary artery smooth muscle cells
Creators
- 1. Ege Univ, Sch Med, Div Nephrol, Dept Internal Med, TR-35100 Izmir, Turkey
- 2. Univ Arkansas Med Sci, Div Nephrol, Dept Internal Med, Little Rock, AR 72205 USA
Description
Aim: Presence of accelerated atherosclerosis in dialysis patients cannot be entirely explained by conventional risk factors. Exposure to urea, which is elevated in patients with kidney disease, leads to the carbamylation of proteins. We investigated the effects of carbamylated low-density lipoprotein (cLDL) on human coronary artery vascular smooth muscle cells (VSMC).
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