Published January 1, 2009 | Version v1
Journal article Open

Effects of Amrinone in an Experimental Model of Hepatic Ischemia-Reperfusion Injury

  • 1. Erciyes Univ, Sch Med, Dept Gen Surg, TR-38039 Kayseri, Turkey
  • 2. Erciyes Univ, Sch Med, Dept Pathol, TR-38039 Kayseri, Turkey
  • 3. Erciyes Univ, Sch Med, Dept Biochem, TR-38039 Kayseri, Turkey

Description

Background. During some surgical interventions, temporary occlusion of the hepatic blood supply may cause ischemia-reperfusion (IR) injury. Recent studies suggest that type 3 phosphodiesterase inhibitors may have a beneficial effect on liver IR injury. The aim of this study was to investigate whether amrinone, a type 3 phosphodiesterase inhibitor, could have a protective effect on liver having experimental liver IR injury.

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