Published January 1, 2008 | Version v1
Journal article Open

Prenatal Expressions of Hyperpolarization-activated Cyclic-Nucleotide-Gated Channel (HCN) Genes in Dysplastic Hippocampi in Rats

  • 1. Bagcilar Training & Res Hosp, Dept Neurosurg, Istanbul, Turkey
  • 2. McGill Univ, Dept Neurosurg, Montreal Neurol Inst, Montreal, PQ H3A 2T5, Canada
  • 3. Bogazici Univ, Dept Mol Biol & Genet, Istanbul, Turkey
  • 4. Istanbul Univ, Cerrahpasa Med Fac, Dept Neurosurg, Istanbul, Turkey
  • 5. Marmara Univ, Fac Med, Dept Histol & Embryol, Istanbul, Turkey

Description

AIM: Hyperpolarization-activated cyclic nucleotide-gated (HCN or h-channel) channels mediate hyperpolarization-activating currents in the hippocampus and neocortex. The aim of this study is to present prenatal h-channel gene expressions (HCN1 and HCN2; HCN1-Entrez-Gene ID: 84390; HCN2- Entrez Gene ID: 114244) in dysplastic hippocampal pyramidal neurons induced by in utero irradiation in rats.

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