Published January 1, 2009
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The Sequential Sonogashira-Click Reaction: A Versatile Route to 4-Aryl-1,2,3-triazoles
- 1. Eotvos Lorand Univ, Dept Organ Chem, Inst Chem, H-1117 Budapest, Hungary
Description
Aryl halides can be easily transformed in a one-pot procedure into 4-aryl-1,2,3-triazoles with palladium/copper-catalyzed Sonogashira-click reaction sequence, using trimethylsilylacetylene as acetylene surrogate.
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