Published January 1, 2009 | Version v1
Journal article Open

Anticandidal Activity of Volatile Compounds from the Root Bark of Ficus exasperata Vahl-Holl (Moraceae)

  • 1. Univ Ibadan, Dept Chem, Ibadan, Nigeria
  • 2. Univ Ilorin, Dept Chem, Ilorin, Nigeria
  • 3. Univ Karachi, ICCBS, HEJ Res Inst Chem, Karachi 75270, Pakistan
  • 4. Ladoke Akintola Univ Technol, Dept Pure & Appl Chem, Ogbomosho, Nigeria

Description

The essential oil from the root bark of Ficus exasperata cultivated in Nigeria were examined by GC and GC-MS. The essential oil was characterized by the presence of alpha-terpineol (33.7%), alpha-pinene (10.8%), sabinene (5.6%), beta-patchoulene (4.7%), 1,8-cineole (3.1%), and alpha-thujopsene (2.1%) as the major compounds. The volatile oil was assessed against clinical strain of Candida albicans. The low minimum inhibition concentration (MIC) of this compound (1.1 mu g/mL) is among the basis of this report.

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