Published January 1, 2008
| Version v1
Journal article
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Development of a Reconstructed Cornea from Collagen-Chondroitin Sulfate Foams and Human Cell Cultures
Creators
- 1. Middle E Tech Univ, BIOMAT, Dept Biol Sci, Biotechnol Res Unit, TR-06531 Ankara, Turkey
- 2. Hosp Civils Lyon, Lyon, France
- 3. Leiter Hornhautbank, Klin & Poliklin Augenheilkunde, Kopf & Hautzentrum, Hamburg, Germany
- 4. Osped Civile Venezia, Veneto Eye Bank Fdn, Venice, Italy
- 5. Univ Lyon, CNRS, Inst Biol & Chim Prot, Lyon, France
Description
PURPOSE. To develop an artificial cornea, the ability to coculture the different cell types present in the cornea is essential. Here the goal was to develop a full-thickness artificial cornea using an optimized collagen-chondroitin sulfate foam, with a thickness close to that of human cornea, by coculturing human corneal epithelial and stromal cells and transfected human endothelial cells.
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