Yayınlanmış 1 Ocak 2008 | Sürüm v1
Dergi makalesi Açık

Development of a Reconstructed Cornea from Collagen-Chondroitin Sulfate Foams and Human Cell Cultures

  • 1. Middle E Tech Univ, BIOMAT, Dept Biol Sci, Biotechnol Res Unit, TR-06531 Ankara, Turkey
  • 2. Hosp Civils Lyon, Lyon, France
  • 3. Leiter Hornhautbank, Klin & Poliklin Augenheilkunde, Kopf & Hautzentrum, Hamburg, Germany
  • 4. Osped Civile Venezia, Veneto Eye Bank Fdn, Venice, Italy
  • 5. Univ Lyon, CNRS, Inst Biol & Chim Prot, Lyon, France

Açıklama

PURPOSE. To develop an artificial cornea, the ability to coculture the different cell types present in the cornea is essential. Here the goal was to develop a full-thickness artificial cornea using an optimized collagen-chondroitin sulfate foam, with a thickness close to that of human cornea, by coculturing human corneal epithelial and stromal cells and transfected human endothelial cells.

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