Published January 1, 2008 | Version v1
Journal article Open

PTEN Expression in Primary Prostate Carcinoma in Turkish Patients

  • 1. Hacettepe Univ, Fac Med, Dept Pathol, TR-06100 Ankara, Turkey
  • 2. Hacettepe Univ, Fac Med, Dept Urol, TR-06100 Ankara, Turkey
  • 3. Hacettepe Univ, Fac Med, Dept Biostat, TR-06100 Ankara, Turkey

Description

Aim: Prostatic adenocarcinoma shows remarkable variability in the incidence and biological behavior between populations from different races and geographical regions of the world. PTEN has been reported as the most commonly mutated tumor suppressor gene in prostate cancer. Incidence of PTEN alterations occurring in prostatic carcinoma has not been studied previously in the Turkish population.

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