Published January 1, 2018 | Version v1
Journal article Open

Midkine downregulation increases the efficacy of quercetin on prostate cancer stem cell survival and migration through PI3K/AKT and MAPK/ERK pathway

  • 1. Trakya Univ, Sch Med, Dept Med Biol, Balkan Campus, TR-22030 Edirne, Turkey
  • 2. Trakya Univ, Sch Med, Dept Med Biochem, Balkan Campus, Edirne, Turkey
  • 3. Istanbul Aydin Univ, Sch Med, Dept Histol & Embryol, Istanbul, Turkey
  • 4. Ege Univ, Sch Med, Dept Histol & Embryol, Izmir, Turkey

Description

Aims: To examine the functions of growth factor midkine (MK) and a flavonoid quercetin on survival, apoptosis and migration of prostate cancer (PCa) stem cells (CSCs).

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