Published January 1, 2018 | Version v1
Journal article Open

The effects of LXR agonist GW3965 on vascular reactivity and inflammation in hypertensive rat aorta

  • 1. Gazi Univ, Fac Pharm, Dept Pharmacol, TR-06330 Ankara, Turkey
  • 2. Karamanoglu Mehmetbey Univ, KO Fac Sci, Dept Biol, Karaman, Turkey
  • 3. Ankara Univ, Fac Med, Dept Med Pharmacol, TR-06100 Ankara, Turkey

Description

Aims: Liver X receptors (LXRs) play an important role in the regulation of cholesterol, fatty acid and glucose metabolisms together with inflammatory processes. In the present study, the effects of LXR agonist GW3965 on vascular reactivity and expression of functional proteins in DOCA-Salt induced hypertension were examined.

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