Published January 1, 2018
| Version v1
Journal article
Open
Exaggerated follicular helper T-cell responses in patients with LRBA deficiency caused by failure of CTLA4-mediated regulation
Creators
- 1. Marmara Univ, Div Pediat Allergy Immunol, Istanbul, Turkey
- 2. King Faisal Specialist Hosp & Res Ctr, Dept Pediat, Riyadh, Saudi Arabia
- 3. King Faisal Specialist Hosp & Res Ctr, Dept Genet, Riyadh, Saudi Arabia
Description
Background: LPS-responsive beige-like anchor protein (LRBA) and cytotoxic T lymphocyte-associated antigen 4 (CTLA4) deficiencies give rise to overlapping phenotypes of immune dysregulation and autoimmunity, with dramatically increased frequencies of circulating follicular helper T (cTFH) cells.
Files
bib-cd1ca2fe-e01d-449a-bbe7-4b19bb60396c.txt
Files
(355 Bytes)
| Name | Size | Download all |
|---|---|---|
|
md5:a3de6d21191184d2540090afe1de9d30
|
355 Bytes | Preview Download |