Yayınlanmış 1 Ocak 2018 | Sürüm v1
Dergi makalesi Açık

Can ursolic acid be beneficial against diabetes in rats?

  • 1. Hacettepe Univ, Fac Pharm, Dept Pharmaceut Toxicol, TR-06100 Ankara, Turkey
  • 2. Bulent Ecevit Univ, Fac Pharm, Dept Pharmaceut Toxiol, Zonguldak, Turkey
  • 3. Ankara Univ, Fac Pharm, Dept Pharmacol, TR-06100 Ankara, Turkey
  • 4. Hacettepe Univ, Fac Pharm, Dept Pharmacognosy, TR-06100 Ankara, Turkey

Açıklama

Objective: Diabetes mellitus, a heteregenous metabolic and chronic disease, is a growing health problem especially in developing countries. It is claimed that diabetes associated with increased formation of free radicals and decrease in antioxidant potential and also alterations in lipid profile and enzyme levels. Ursolic acid is commonly used in traditional Chinese medicine due to its beneficial effects. The aim of this study was to investigate the effects of ursolic acid on streptozotocin-induced diabetes in Wistar albino rats.

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