Published January 1, 2018 | Version v1
Journal article Open

Realizing drug repositioning by adapting a recommendation system to handle the process

  • 1. Middle East Tech Univ, Dept Comp Engn, Ankara, Turkey
  • 2. TOBB Univ, Dept Comp Engn, Ankara, Turkey
  • 3. Univ Calgary, Dept Comp Sci, Calgary, AB, Canada

Description

Background: Drug repositioning is the process of identifying new targets for known drugs. It can be used to overcome problems associated with traditional drug discovery by adapting existing drugs to treat new discovered diseases. Thus, it may reduce associated risk, cost and time required to identify and verify new drugs. Nowadays, drug repositioning has received more attention from industry and academia. To tackle this problem, researchers have applied many different computational methods and have used various features of drugs and diseases.

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