Yayınlanmış 1 Ocak 2018
| Sürüm v1
Dergi makalesi
Açık
Genotype and Allele Frequency of CYP3A4-392A > G in Turkish Patients with Major Depressive Disorder
Oluşturanlar
- 1. Mersin Univ, Fac Pharm, Dept Pharmaceut Toxicol, Mersin, Turkey
- 2. Ankara Univ, Dept Psychiat, Fac Med, Ankara, Turkey
- 3. Kirikkale Univ, Fac Med, Dept Psychiat, Kirikkale, Turkey
- 4. Ankara Univ, Fac Pharm, Dept Toxicol, Ankara, Turkey
Açıklama
Objectives: Genetic polymorphisms may help for individualized drug dosing and improved therapeutics. CYP3A4 is responsible for the metabolism of more than 50% of the commonly used drugs and metabolizes typical antipsychotic medications and antidepressant drugs. The objective of the study was to assess the genotype and allele frequencies of CYP3A4 -392A>G in Turkish patients with major depressive disorder receiving any SSRIs and to compare these results with the frequencies of other ethnic groups.
Dosyalar
10-4274-tjps-46320.pdf
Dosyalar
(246.9 kB)
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