Yayınlanmış 1 Ocak 2018
| Sürüm v1
Dergi makalesi
Açık
Discovering lncRNA mediated sponge interactions in breast cancer molecular subtypes
Oluşturanlar
- 1. Bilkent Univ, Dept Comp Engn, TR-06800 Ankara, Turkey
- 2. Bilkent Univ, Fac Sci, Dept Mol Biol & Genet, TR-06800 Ankara, Turkey
- 3. Sabanci Univ, Fac Engn & Nat Sci, TR-34956 Istanbul, Turkey
Açıklama
Background: Long non-coding RNAs (lncRNAs) can indirectly regulate mRNAs expression levels by sequestering microRNAs (miRNAs), and act as competing endogenous RNAs (ceRNAs) or as sponges. Previous studies identified lncRNA-mediated sponge interactions in various cancers including the breast cancer. However, breast cancer subtypes are quite distinct in terms of their molecular profiles; therefore, ceRNAs are expected to be subtype-specific as well.
Dosyalar
bib-6239a5ba-8606-45b9-b5da-93f7b7fb521a.txt
Dosyalar
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