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Published January 1, 2020 | Version v1
Journal article Open

Phenotypic and Molecular Detection of the Metallo-Beta-Lactamases in Carbapenem-Resistant Pseudomonas aeruginosa Isolates from Clinical Samples

Creators

  • 1. Omer Halisdemir Educ & Training Hosp, Med Microbiol Dept, Nigde, Turkey
  • 2. Mersin Univ, Fac Med, Med Microbiol Dept, Mersin, Turkey
  • 3. Dezenkon Kimya Co, Ankara, Turkey
  • 4. Mersin Univ, Fac Pharm, Pharmaceut Microbiol Dept, Mersin, Turkey

Description

Background: Pseudomonas aeruginosa is an opportunistic pathogen that causing high morbidity and mortality, and responsible for a high proportion of hospital infections. Recently, P. aeruginosa infections having carbapenem group antibiotic-resistant have been increasing and serious problems are being experienced in treatment. Carbapenem resistance mechanisms are the loss of OprD porin protein, excretion of drug with the efflux system and production of metallo-beta-lactamase (MBL).

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