Yayınlanmış 1 Ocak 2020
| Sürüm v1
Dergi makalesi
Açık
Evaluation of T Lymphocyte Subgroups in Patients with Chronic Lymphocytic Leukemia
Oluşturanlar
- 1. Istanbul Univ, Aziz Sancar Deneysel Tip Arastirma Enstitusu, Immunol Anabilim Dali, Istanbul 34393, Turkey
- 2. Istanbul Univ, Istanbul Tip Fak, Ic Hastaliklari Anabilim Dali, Hematol Bilim Dali, Istanbul, Turkey
Açıklama
Introduction: Chronic lymphocytic leukemia (CLL) that arises by malignant transformation of mature B cell is the most common leukemia in elderly. CLL is characterized by accumulation of CD5(+)CD19(+) cells in the peripheral blood and lymphoid organs. While CD8(+) T lymphocytes response intracellular pathogen and tumor, CD4(+) T lymphocytes regulate immune response. T follicular (Tfol) cells stimulate affinity maturation and class-switch recombination in B lymphocytes due to cytokine and surface molecules. In this study, we aimed to investigate CD4(+)T, CD8(+)T and CD3(+)CD4(+)CXCR5(+) follicular T (Tfol) cells in the peripheral blood of the CLL patients compared to healthy controls.
Dosyalar
10-25002-tji-2020-1240.pdf
Dosyalar
(1.5 MB)
| Ad | Boyut | Hepisini indir |
|---|---|---|
|
md5:5bf5ee26eb4d057ab78f719c29820cb8
|
1.5 MB | Ön İzleme İndir |