Published January 1, 2018
| Version v1
Journal article
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Discovery of new Toxoplasma gondii antigenic proteins using a high throughput protein microarray approach screening sera of murine model infected orally with oocysts and tissue cysts
Creators
- 1. Ege Univ, Fac Med, Dept Parasitol, Vaccine Res & Dev Lab, Bornova, Turkey
- 2. Univ Calif Irvine, Dept Med, Div Infect Dis, Irvine, CA 92717 USA
- 3. Ege Univ, Dept Mol Biol, Fac Sci, Bornova, Turkey
- 4. Ege Univ, Dept Bioengn, Fac Engn, Bornova, Turkey
Description
Background: Toxoplasma gondii is an obligate intracellular protozoan parasite that causes congenital toxoplasmosis, as well as other serious clinical presentations in immune compromised humans. The parasite has also been recently linked to behavioral diseases in humans and other mammalian hosts. New antigens are being evaluated to develop a diagnostic kit for the diagnosis of acute infection or a protective vaccine.
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