Published January 1, 2020 | Version v1
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Design, Synthesis, and In vitro Evaluation of Thieno[a]dibenzothiophene Derivatives

  • 1. Van Yuzuncu Yil Univ, Dept Mol Biol & Genet, TR-65080 Van, Turkey
  • 2. Van Yuzuncu Yil Univ, Dept Chem, TR-65080 Van, Turkey
  • 3. Ondokuz Mayis Univ, Fac Agr, Dept Agr Biotechnol, TR-55139 Samsun, Turkey

Description

A variety of highly substituted thieno[2,3-a]dibenzothiophenes and thieno[3,2-a]dibenzothiophenes are readily prepared via cascade electrophilic cyclization reaction. The reaction was tolerated a variety of compounds. In the present study, antimicrobial and antifungal activities were investigated for all synthesized molecules against A. niger ATCC 16404, C. albicans ATCC 10231, S. aureus ATCC 25923 and B. subtilis ATCC 6633, respectively.

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