Published January 1, 2018 | Version v1
Journal article Open

Protective effects of L-theanine against doxorubicin-induced nephrotoxicity in rats

  • 1. Ardahan Univ, ND Gole Vocat High Sch, Program Laborant & Vet Hlth, Ardahan, Turkey
  • 2. Karadeniz Tech Univ, Fac Med, Dept Med Biochem, Trabzon, Turkey
  • 3. Ardahan Univ, Fac Hlth, Dept Nursing, Ardahan, Turkey
  • 4. Karadeniz Tech Univ, Fac Med, Dept Histol & Embryol, Trabzon, Turkey
  • 5. Karadeniz Tech Univ, Fac Med, Dept Pathol, Trabzon, Turkey

Description

Background/aim: L-theanine is the unique amino acid found in tea plants, has antioxidant and antiinflammatory activities, and functions in mental concentration and sleep quality. In this study, it is aimed to investigate the effects of L-theanine on doxorubicin (DOX, a chemotherapeutic agent) induced nephrotoxicity in rats, especially via GSH related enzymes.

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