Published January 1, 2024 | Version v1
Journal article Open

New Synthesis of Some Isoxazole Derivatives and Their Antioxidant Properties

Creators

  • 1. Univ Namik Kemal, Fac Art & Sci, Dept Chem, TR-59030 Tekirdag, Turkiye

Description

A series of substituted ethyl 5-phenyl-1,2-oxazole-3-carboxylates were synthesized in good to excellent yields in one step using hydroxylamine base and ethyl 2,4-dioxo-4-(4-R-phenyl)butanoates bearing both electron-donating and electron-withdrawing moieties on the benzene ring, and antioxidant properties of the products were investigated by the DPPH method. The proposed method is suitable for the large-scale production of isoxazole derivatives.

Files

bib-d41b6146-4de5-46fc-99d5-4ba9bd8f284b.txt

Files (152 Bytes)

Name Size Download all
md5:6b62aa64bc52e3c57839246e609022af
152 Bytes Preview Download