Published January 1, 2010 | Version v1
Journal article Open

Effect of prolonged administration of bovine lactoferrin in neuropathic pain: Involvement of opioid receptors, nitric oxide and TNF-alpha

  • 1. Ege Univ, Fac Med, Dept Pharmacol & Clin Pharmacol, TR-35100 Izmir, Turkey
  • 2. Ege Univ, Fac Med, Dept Anat, TR-35100 Izmir, Turkey
  • 3. Ege Univ, Fac Med, Dept Physiol, TR-35100 Izmir, Turkey

Description

Aims: This study aimed to investigate the effect of prolonged administration of bovine milk lactoferrin (bLF) on hyperalgesia and allodynia in a rat model of neuropathic pain and to determine the involvement of c-Fos, TNF-alpha, nitric oxide and opioidergic systems in this effect.

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