Published January 1, 2010
| Version v1
Journal article
Open
Facile Synthesis of Novel Pyrimido[1,2-a]pyrimidin-4-ones from Highly Reactive Malonates
- 1. Ankara Univ, Fac Sci, Dept Chem, TR-06100 Ankara, Turkey
Description
A very simple and efficient procedure for the synthesis of novel 2-hydroxy-4H-pyrimido[1,2-a]pyrimidin-4-ones is described. Title compounds were obtained from the room temperature reaction of 2-aminopyrimidine and its substituted derivatives with bis(2,4,6-trichlorophenyl) malonates. High product yields were observed under optimized conditions. Applicability and reactivity of a range of substituted and unsubstituted phenyl malonates were also investigated. Structural identification of all new compounds was accomplished by spectroscopic methods and elemental analysis.
Files
bib-9ed89d77-a11f-44d8-adb8-cdfea8a64a2d.txt
Files
(197 Bytes)
| Name | Size | Download all |
|---|---|---|
|
md5:27b37ecd46a4cb4b35e9d65acde849e3
|
197 Bytes | Preview Download |