Published January 1, 2010
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Potassium-Tertiary Butoxide-Assisted Addition of Thioglicolic Acid to Chalcone Derivatives Under Solvent-Free Conditions
- 1. Gaziosmanpasa Univ, Dept Chem, Fac Arts & Sci, TR-60110 Tokat, Turkey
Description
A series of chalcone derivatives containing thioglicolic acid (4a-j) was prepared by addition of thioglicolic acid to the chalcones (3a-j) in the presence of KOt-Bu under solvent-free conditions. The mechanistic pathway of the reaction can be explained by the Michael-type addition of thioglicolic acid to chalcone derivatives (3a-j).
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