Published January 1, 2024
| Version v1
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Identification of Sars-Cov-2 related volatile organic compounds from face masks
Creators
- 1. Mehmet Akif Ersoy Univ, Fac Sci & Literature, Dept Analyt Chem, Burdur, Turkiye
- 2. Ankara Univ, Fac Vet Med, Dept Biochem, Ankara, Turkiye
- 3. Mehmet Akif Ersoy Univ, Fac Sci & Literature, Dept Anorgan Chem, Burdur, Turkiye
- 4. Diskapi Yildirim Beyazit Teaching & Res Hosp, Clin Infect Dis & Microbiol, Ankara, Turkiye
- 5. Ankara Univ, Fac Vet Med, Dept Microbiol, Ankara, Turkiye
- 6. Ankara Univ, Fac Vet Med, Dept Biometr, Ankara, Turkiye
- 7. Ankara Univ, Fac Vet Med, Dept Physiol, Ankara, Turkiye
- 8. Duzce Univ, Fac Med, Dept Biochem, Duzce, Turkiye
- 9. Duzce Univ, Fac Med, Dept Infect Dis, Duzce, Turkiye
- 10. Ankara Univ, Fac Vet Med, Dept Genet, Ankara, Turkiye
- 11. Duzce Univ, Fac Med, Dept Microbiol, Duzce, Turkiye
- 12. Ankara Univ, Fac Vet Med, Dept Virol, Ankara, Turkiye
Description
This study aims to identify SARS-CoV-2-related volatile organic compounds (VOCs) of the exhaled breath from face masks. Face masks collected from SARS-CoV-2 patients (n = 30) and the control group (n = 11) were analyzed to detect VOCs in the exhaled breath using the Headspace-Gas Chromatography Mass Spectrometry. Significant increases in concentrations of toluene, hexadecane, and phenol were detected in the face masks belonging to patient groups (p < 0.001). Clinical sig-nificance was further found in isobutyric acid levels considering Cohen's d value (p = 0.070). The findings of this study suggest that monitoring toluene, hexadecane, phenol, and isobutyric acid could provide considerable support in rapid screening of SARS-CoV-2.
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