Published January 1, 2010
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Politamide, a new constituent from the stem bark of Ficus polita Vahl (Moraceae)
Creators
- 1. Univ Yaounde I, Dept Organ Chem, POB 812, Yaounde, Cameroon
- 2. Fac Med & Biomed Sci, Dept Pharm & Tradit Pharmacopeia, Yaounde, Cameroon
- 3. Yamagata Univ, Dept Bioresource Engn, Fac Agr, Yamagata 9978555, Japan
- 4. Univ Henri Poincare, Lab Methodol RMN, Inst Jean Barriol, Fac Sci, F-54506 Vandoeuvre Les Nancy, France
- 5. Univ Versailles St Quentin en Yvelines, Lab Genet & Biol Cellulaire, F-78035 Versailles, France
- 6. Univ Paul Verlaine Metz, Lab Ingn Mol & Biochim Pharmacol, Inst Jean Barriol, F-57070 Metz, France
Description
A new cerebroside 1 characterized as (2R,9Z)-2-hydroxy-N-{(1S,2S,3R,4S)-1-[(beta-D-glucopyranosyloxy)methyl]-2,3,4-trihydroxyoctacosan-1-yl}-9-pentadecenamide was isolated from the stem bark of Ficus polita Vahl ( Moraceae) together with four known compounds identified as sitosterol 3-O-beta-D-glucopyranoside 2, betulinic acid 3, stigmasterol 4 and lupeol 5. Their structures were determined on the basis of spectroscopic methods as well as HR-ESI-MS, NMR analyses, chemical transformation, and by comparison of their physical and spectral data with those reported in the literature and with authentic specimens for some known compounds.
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