Published January 1, 2022
| Version v1
Journal article
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Could lysosomal acid lipase enzyme activity be used for clinical follow-up in cryptogenic cirrhosis?
Creators
- 1. Ankara Univ, Dept Pediat Metab, Fac Med, Ankara, Turkey
- 2. Dokuz Eylul Univ, Int Biomed & Genome Inst, Dept Mol Biol & Genet, Izmir, Turkey
- 3. Int Biomed & Genome Ctr, Dept Basic & Translat Res, Izmir, Turkey
- 4. Dokuz Eylul Univ, Dept Pediat Metab, Fac Med, Izmir, Turkey
- 5. Dokuz Eylul Univ, Dept Gastroenterol, Fac Med, Izmir, Turkey
- 6. Dokuz Eylul Univ, Dept Med Biol, Fac Med, Izmir, Turkey
- 7. Dokuz Eylul Univ, Dept Chem Sci, Izmir, Turkey
Description
Background/aim: Cholesterol ester storage disease (CESD) is one of the rare causes that should be kept in mind in the etiology of cirrhosis. Recent studies detected that significantly reduced lysosomal acid lipase deficiency enzyme (LAL) in patients with cryptogenic cirrhosis (CC). Moreover, studies have evaluated that LAL activity is as effective as scoring systems in assessing the severity of cirrhosis.
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