Published January 1, 2022
| Version v1
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Therapeutic potential of conditioned medium obtained from deferoxamine preconditioned umbilical cord mesenchymal stem cells on diabetic nephropathy model
Creators
- 1. Istanbul Univ Cerrahpasa, Cerrahpasa Fac Med, Histol & Embryol Dept, Kocamustafapasa St, TR-34098 Istanbul, Turkey
- 2. Istanbul Univ, Fac Sci, Biol Dept, Mol Biol Sect, Istanbul, Turkey
- 3. Istanbul Univ Cerrahpasa, Cerrahpasa Fac Med, Med Biochem Dept, Istanbul, Turkey
- 4. Istanbul Univ, Drug Applicat & Res Ctr, Fac Pharm, Istanbul, Turkey
- 5. Istanbul Univ Cerrahpasa, Cerrahpasa Fac Med, Obstet & Gynecol Dept, Istanbul, Turkey
Description
Background: The therapeutic potential of mesenchymal stem cells (MSCs)-derived conditioned media (CM) can be increased after preconditioning with various chemical agents. The aim of this study is comparative evaluation of effects of N-CM and DFS-CM which are collected from normal (N) and deferoxamine (DFS) preconditioned umbilical cord-derived MSCs on rat diabetic nephropathy (DN) model.
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