Published January 1, 2022
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Synthesis of Nanoparticles Loading Indenopyrazole Derivatives and Evaluation of Biological Features
- 1. Sivas Cumhuriyet Univ, Dept Pharmaceut Biotechnol, Fac Pharm, Sivas, Turkey
- 2. Sivas Cumhuriyet Univ, Dept Biochem, Fac Pharm, Sivas, Turkey
- 3. Sivas Cumhuriyet Univ, Fac Hlth Sci, Dept Nutr & Dietet, Sivas, Turkey
Description
Objective: In this study, it was aimed to prepare nanoparticle formulations using chitosan, a cationic natural polymer, and tripoly phosphate, and to perform mechanical characterization and in vitro cell culture studies. In addition, the cytotoxic effects of nanoparticles containing indenopyrazol derivatives against human glioma cells (C6) and human cervical cancer cells (HeLa) were investigated.
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