Yayınlanmış 1 Ocak 2022
| Sürüm v1
Dergi makalesi
Açık
Chloroquine Decreased Kir6.2 Immunoreactivity in Chronic Hypoxic Heart
Oluşturanlar
- 1. Yozgat Bozok Univ, Fac Med, Yozgat, Turkey
- 2. Yozgat Bozok Univ, Fac Med, Dept Histol & Embryol, Yozgat, Turkey
- 3. Erciyes Univ, Fac Sci, Dept Biol, Kayseri, Turkey
- 4. Erciyes Univ, Fac Med, Dept Physiol, Kayseri, Turkey
- 5. Pamukkale Univ, Fac Med, Dept Histol & Embryol, Denizli, Turkey
- 6. Erciyes Univ, Fac Med, Dept Histol & Embryol, Kayseri, Turkey
- 7. Univ Hlth Sci Turkey, Int Med Fac, Dept Biophys, Istanbul, Turkey
Açıklama
Objective: Experimental and clinical studies indicate that cardiovascular system diseases have the highest mortality rate. One of the major factors underlying this high mortality rate is hypoxia. The inward rectifying potassium channel 6.2 (Kir6.2) plays a key role in the adaptation and metabolic regulation of cardiac tissue to hypoxia. In this study, the effect of chloroquine on Kir6.2 expression in heart tissue exposed to moderate chronic hypoxia was investigated.
Dosyalar
10-14235-bas-galenos-2021-5543.pdf
Dosyalar
(1.2 MB)
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